Golgi Apparatus: Architecture, Functions and Role in Disease

ISBN : 9781639899043

Author : Thomas Bellissimo

Publisher : States Academic Press

Year : 2025

Language : English

Type : Book

Description : Golgi apparatus is a crucial organelle in eukaryotic cells and functions as a central processing and distribution center in the cell's endomembrane system. Structurally, it consists of stacks of membrane-bound sacs called cisternae, which are involved in modifying, sorting, and packaging proteins and lipids received from the endoplasmic reticulum (ER). The Golgi apparatus plays a pivotal role in cellular transportation and secretion. It modifies proteins through processes such as glycosylation and phosphorylation, thereby directing them to specific cellular destinations. Additionally, it packages these modified proteins into vesicles for transport to various organelles within or out of the cell. Overall, the Golgi apparatus is essential for maintaining cellular homeostasis, signaling, and secretion, making it integral to the proper functioning of eukaryotic cells. This book covers in detail some existent theories and innovative concepts revolving around Golgi apparatus architecture, functions and its role in disease control. The book aims to shed light on some of the unexplored mechanisms of Golgi complex and the recent researches in this field. This book, with its detailed analyses and data, will prove immensely beneficial to professionals and students involved in this area at various levels.

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