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Book

Flavonoids and Anti-Aging : The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2

ISBN : 9781032125732

Author : Karam F.A. Soliman

Publisher : CRC Press

Year : 2023

Language : English

Type : Book

Description : The nuclear factor erythroid 2-related factor 2 (Nrf2) was described as a master regulator of the cellular antioxidant response. Moreover, many critical biological functions linked to cell viability, metabolism, autophagy, inflammation, immunity, and differentiation have been attributed to Nrf2, which regulates over 600 genes. It is well known that oxidative stress, which Nrf2 can ameliorate, plays a key role in many pathologic processes such as aging, obesity, diabetes, cancer, and neurodegenerative diseases.

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